成果公開

論文発表

2017年

Aoki, K., Kondo, Y., Naoki, H., Hiratsuka, T., Itoh, R.E., Matsuda, M.
Propagating Wave of ERK Activation Orients Collective Cell Migration.
Developmental Cell, 43, pp305-317. (2017)

Uda, Y., Goto, Y., Oda, S., Kohchi, T., Matsuda, M., and Aoki, K.
Efficient synthesis of phycocyanobilin in mammalian cells for optogenetic control of cell signaling.
PNAS, doi: 10.1073/pnas.1707190114, (2017)

Arata, M., Sugimura, K. and Uemura, T.
Difference in Dachsous levels between migrating cells coordinates the direction of collective cell migration.
Developmental Cell, in press.

2016年

Kamino, K. and Kondo, Y.
Rescaling of spatio-temporal sensing in eukaryotic chemotaxis.
PLoS ONE 11(10): e0164674 (2016)

Naoki, H., Nishiyama, M., Togashi, K., Igarashi, Y., Hong, K., Ishii, S.
Multi-phasic bi-directional chemotactic responses of the growth cone.
Sci Rep 6, 36256 (2016)

Yamao, M., Aoki, K., Yukinawa, N., Ishii, S., Matsuda, M., Naoki, H.
Two new FRET imaging measures: linearly proportional to and highly contrasting the fraction of active molecules.
PLoS ONE 11(10), e0164254 (2016)

Li, Y., Nakae, K., Ishii S., Naoki, H.
Uncertainty-dependent Extinction of Fear Memory in an Amygdala-mPFC Neural Circuit Model.
PLOS Computational Biology 12(9): e1005099l(2016)

Kanatsu-Shinohara, M., Naoki, H., Shinohara, T.
Nonrandom germline transmission of mouse spermatogonial stem cells.
Dev Cell, 2016, 38; 248–261
京都大学の広報ニュースは「こちら」です。

Tsukada, Y., Yamao, M., Naoki H, Shimowada, T., Ohnishi, N., Kuhara, A., Ishii, S., & Mori, I.
Reconstruction of spatial thermal gradient encoded in thermosensory neuron AFD in Caenorhabditis elegans.
J Neurosci, 2016 36(9); 2571-2581

M. Holden, Aoki, K., Matsuda, M.
Method of Quantifying Active State FRET Populations from Intensity Images.
Focus on Microscopy 2016, Teipei, Taiwan, March 20-23, 2016

M. Holden.
A linear measure of Forster resonant energy transfer (FRET) efficiency incorporating a shot noise uncertainty model for fluorescence microscopy intensity images.
International Symposium on Biomedical Imaging 2016, Prague, Czech Republic, April 13-16, 2016

2015年

Shikauchi, Y., Ishii, S.
Decoding the view expectation during learned maze navigation from human fronto-parietal network.
Sci Rep, 2015, srep17648
京都大学の広報ニュースは「こちら」です。

Yamao, M., Naoki, H., Kunida, K., Aoki, K., Matsuda, M., Ishii, S.
Distinct predictive performance of Rac1 and Cdc42 in cell migration.
Sci Rep, 2015, srep17527

Aoki, K.
Visualization of Intracellular Signaling with Fluorescence Resonance Energy Transfer-Based Biosensors.
Protein Modifications in Pathogenic Dysregulation of Signaling, 2015, Springer, 31-41

Komatsubara, A.T., Matsuda, M., Aoki, K.
Quantitative analysis of recombination between YFP and CFP genes of FRET biosensors introduced by lentiviral or retroviral gene transfer.
Sci Rep, 2015, 5; 13283

Komatsu, N., Fujita, Y., Matsuda, M., Aoki, K. (corresponding author)
mTORC1 upregulation via ERK-dependent gene expression change confers intrinsic resistance to MEK inhibitors in oncogeneic KRas-mutant cancer cells.
Oncogene, 2015, in press

2014年

M. Holden, Hiratsuka, T., Matsuda, M., Nakao, M.
Detection of platelet signalling using FRET biosensors and time-lapse fluorescence microscopy.
Focus on Microscopy 2014, Sydney, Australia, April 13-16, 2014

Hirashima, T.
Pattern Formation of an Epithelial Tubule by Mechanical Instability during Epididymal Development.
Cell Reports, 2014, in press

Sadaie, W., Harada, Y., Matsuda, M., Aoki, K.
Quantitative in vivo fluorescence cross-correlation analyses highlight the importance of competitive effect in the regulation of protein-protein interactions.
Mol Cell Biol, 2014, 34; 3272-90
解説はこちら

Fujita, Y., Komatsu, N., Matsuda, M., Aoki, K.
FRET-based quantitative analysis of feedforward and feedback loops in EGFR signaling and the sensitivity to molecular targeting drugs.
FEBS Journal, 2014, 281; 3177-92
解説はこちら

Morioka, H., Kanemura, A., Morimoto, S., Yoshioka, T., Oba, S., Kawanabe, M., & Ishii, S.
Decoding spatial attention by using cortical currents estimated from electroencephalography with near-infrared spectroscopy prior information.
NeuroImage. 2014; 90: 128-139

Shimono, K., Fujishima, K., Nomura, T., Ohashi, M., Usui, T., Kengaku, M., Toyoda, A., & Uemura, T.
An evolutionarily conserved protein CHORD regulates scaling of dendritic arbors with body size.
Sci Rep. 2014 Mar 19;4:4415. doi: 10.1038/srep04415.

Tanaka, T., Nagashima, K., Inagaki, N., Kioka, H., Takashima, S., Fukuoka, H., Noji, H., Kakizuka, A., Imamura, H.
Glucose-stimulated single pancreatic islets sustain increased cytosolic ATP levels during initial Ca2+ influx and subsequent Ca2+ oscillations.
J Biol Chem. 2014; 289(4): 2205-16.

2013年

Tsuyama, T., Kishikawa, J., Han, Y. W., Harada, Y., Tsubouchi, A., Noji, H., Kakizuka, A., Yokoyama, K., Uemura, T., Imamura, H.
In vivo fluorescent adenosine 5’-triphosphate (ATP) imaging of Drosophila melanogaster and Caenorhabditis elegans by using a genetically encoded fluorescent ATP biosensor optimized for low temperatures.
Anal Chem. 2013; 85(16): 7889-96.

Aoki, K., Kumagai, Y., Komatsu, N., Fujita, Y., Shionyu, C., Matsuda, M.
Stochastic ERK activation induced by noise and cell-cell propagation regulates cell density-dependent proliferation.
Mol Cell. 2013, 52; 529-40
京都大学の広報ニュースは「こちら」です。

Aoki, K., Takahashi, K., Kaizu, K., Matsuda, M.
A Quantitative Model of ERK MAP Kinase Phosphorylation in Crowded Media.
Sci Rep. 2013 Mar 26;3:1541. doi: 10.1038/srep01541

Aoki, K., Kamioka, Y., Matsuda, M.
Fluorescence resonance energy transfer imaging of cell signaling from in vitro to in vivo: Basis of biosensor construction, live imaging, and image processing.
Dev Growth Differ. 2013 Feb 7. doi: 10.1111/dgd.12039

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